Is one-way cheaper than a return ticket?

It depends on the route and dates — sometimes booking two separate one-ways (possibly with different airlines) beats a return fare, sometimes a return is cheaper even if you only need one direction. Compare both directly rather than assuming.

What's the cheapest day to fly one-way from Chicago to Palermo?

We don't have enough real fare data yet to identify a cheapest weekday for this route.

Which airlines fly this route?

We don't have confirmed airline data for this route yet.

Can I book a one-way ticket with any airline?

Yes — nearly all airlines sell one-way tickets, though low-cost carriers are typically built around one-way pricing by default, while some full-service airlines price one-ways closer to half the return fare rather than a genuine discount.

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One-Way Flights: Chicago to Palermo

Find one-way flights from Chicago to Palermo. No return ticket needed. Flight time: 9h 58m.

One-way vs return tickets: Chicago to Palermo

One-way flights on the Chicago to Palermo route can sometimes be cheaper than booking a return, particularly if you're flexible on the return date or plan to fly back from a different city. Compare the real one-way fares below against a return search to see which works out cheaper for your dates.